organ care system (ocs) heart (TransMedics)

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TransMedics organ care system (ocs) heart
Organ Care System (Ocs) Heart, supplied by TransMedics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/organ+care+system+(ocs)/organ+care+system/pm40645313-33-1-6
Average 90 stars, based on 1 article reviews

organ care system (ocs) heart - by Bioz Stars, 2026-09

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Article Title: Current and Future State of Advanced Heart and Lung Failure Therapies: Highlights From the International Society for Heart and Lung Transplantation 45th Annual Meeting and Scientific Sessions.
Article Snippet: The International Society for Heart and Lung Transplantation (ISHLT) held its 45th annual meeting in Boston, Massachusetts, USA, from April 27th to April 30th, 2025.. As the foremost interdisciplinary global collaborative toward advancing the field, the annual meeting brought together leading researchers and innovators to share insights into the complex management of advanced heart and lung failure therapies and groundbreaking developments in heart and lung transplantation.. For our readers of Artificial Organs, we provide highlights from the ISHLT annual meeting, focusing on the current state and future direction of thoracic transplantation alongside advances in organ preservation technologies and mechanical circulatory support (MCS).

Article Title: Innovative approaches to organ preservation in heart transplantation: A comprehensive review by the French Society of Thoracic and Cardiovascular Surgery.
Article Snippet: Improved approaches for organ preservation have been recently applied in heart transplantation to prevent the risk of primary graft dysfunction.. To review heart-graft preservation systems and to identify criteria for using innovative devices in each specific situation.. A working group of the French Society of Thoracic and Cardiovascular Surgery performed a literature review focusing on organ preservation and post-transplant outcomes.

Article Title: New Techniques for the Optimization of Donor Lungs/Hearts.
Article Snippet: The alternative to both SCS and HOPE is to preserve heart and lung allografts in a functioning, normothermic state.54,55 A platform for EVHP has been developed and is in clinical use (Organ Care System [OCS]; Transmedics).

Article Title: Improving Cardiac Resilience to Ischemia/Reperfusion: The Role of Butyrate in Mitochondrial and Metabolic Recovery
Article Snippet: Our recent findings demonstrate that with the currently used clinical EVHP system, the Organ Care System (OCS, TransMedics Inc.), time-dependent metabolic changes contribute to progressive cardiac dysfunction, thereby highlighting the importance of addressing overall metabolic health during EVHP is crucial to improvise transplant function and viability – .

Preserving:

Article Title: Risk and Reward: Nationwide Analysis of Cardiac Transplant Center Variation in Organ Travel Distance and the Effects on Outcomes.
Article Snippet: Background: The 2018 UNOS allocation policy change deprioritized geographic boundaries to organ distribution, and the effects of this change have been widespread.. The aim of this investigation was to analyze changes in donor transplant center distance for organ travel and corresponding outcomes before and after the allocation policy change.. Methods: The UNOS database was utilized to identify all adult patients waitlisted for heart transplants from 2016 to 2021.

Ex Situ:

Article Title: Donor Heart Preservation for Heart Transplantation: Single-Center Experience with Three Different Techniques.
Article Snippet: .. Among these, the Organ Care System (OCS; TransMedics Inc., Andover, MA, USA), perfusing the donor heart with a normothermic enriched solution of oxygenated donor blood, allows both a significant reduction in graft ischemic time and continuous ex situ assessment of graft perfusion and metabolism. .. Another method currently used for graft preservation is the Paragonix SherpaPak device (PSP; Paragonix Technologies, Inc., Cambridge, MA, USA) which ensures a uniform cooling of the organ at a relatively constant temperature between 4 and 8 ◦C, thus minimizing the risk of ice-cold temperature exposure.

Transplantation Assay:

Article Title: The impact of technology—use of hypothermic machine perfusion: the next standard of care for controlled donation after circulatory death allograft preservation?
Article Snippet: .. Normothermic perfusion on the Organ Care System (OCS, Transmedics, Massachusetts, USA) was used for resuscitation and assessment of the donor hearts prior to transplantation. ..

Ex Vivo:

Article Title: Survival, function, and immune profiling after beating heart transplantation.
Article Snippet: Methods: This was a single-institution retrospective study of adult patients who underwent heart transplantation using ex vivo heart perfusion (EVHP) and a beating heart implantation technique between October 2022 and March 2024.. Primary outcomes of interest included survival, initiation of mechanical circulatory support, and rejection.. A subanalysis of our institutional series of nonbeating deceased after circulatory death (DCD) heart transplantations was performed as well.

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